A mutation screening of oncogenes, tumor suppressor gene TP53 and nuclear encoded mitochondrial complex I genes in oncocytic thyroid tumors

Table 2 Oncogenes altered in oncocytic thyroid tumors

Oncogene	Type of mutation	Type of change	Number of oncogenic events^a
RET/PTC	rearrangement	RET/PTC1	1/26
PAX8-PPARγ	rearrangement	---	5/10
RAS (H-RAS, K-RAS, and N-RAS)	point mutation	p.61 Gln > Arg (Q61R H-, N-, and K-RAS)	3/45
BRAF	point mutation	p.600Val > Glu (V600E)	2/45

^aTotal numbers of tested samples are different, since the different analyses were not possible in all tissues.

ISSN: 1471-2407