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Table 6 Prognostic impact of serum angiogenic factors

From: Association of angiogenic factors with prognosis in esophageal cancer

Serum factor Median   n % Median survival (IQR) 95% CI 3-Y-S (%) p value
G-CSF 35,7 ≤ Median 41 55,4% 23,0 (12,8;*) 12,8 - 33,2 40,6% p = 0,669
   > Median 32 43,2% 30,6 (16,0;*) 16,2 - 45,0 43,5%  
PECAM-1 3243,5 < Median 37 50,0% 29,1 (12,8;*) 17,1 - 41,1 44,5% p = 0,994
   > Median 37 50,0% 28,5 (17,0;*) 12,3 - 44,7 40,8%  
HGF 979,7 ≤ Median 37 50,0% 30,6 (12,8;*) 12,9 - 48,3 43,0% p = 0,871
   > Median 36 48,6% 28,5 (13,7;*) 15,7 - 41,3 41,1%  
VEGF 37,1 < Median 36 48,6% 23,0 (12,3;*) 12,9 - 33,1 39,8% p = 0,590
   > Median 36 48,6% 33,7 (16,0;*) 14,8 - 52,6 44,3%  
Leptin 1492,7 ≤ Median 37 50,0% 30,6 (14,0;*) 16,5 - 44,7 43,5% p = 0,800
   > Median 36 48,6% 28,5 (11,6;*) 10,0 - 47,0 41,6%  
PDGF-BB 1275,1 < Median 37 50,0% 23,8 (12,3;*) 14,3 - 33,3 39,6% p = 0,396
   > Median 37 50,0% 36,7 (18,8;*) - 46,2%  
Angiopoietin-2 867,0 ≤ Median 37 50,0% 29,1 (16,0;*) 18,8 - 39,4 44,7% p = 0,606
   > Median 36 48,6% 28,5 (11,6;*) 11,2 - 45,8 39,7%  
Follistatin 200,37 < Median 37 50,0% 30,6 (16,0;*) - 47,4% p = 0,416
   > Median 37 50,0% 23,8 (12,8;*) 7,1 - 40,5 38,3%  
IL-8 11,86 < Median 37 50,0% n.r. - 51,5% p = 0,143
   > Median 37 50,0% 21,7 (12,3;*) 17,3 - 26,1 32,6%  
Ang-2/VEGF-Ratio 21,9 < Median 36 48,6% 33,7 (19,1;*) 14,9 - 52,5 44,3% p = 0,379
   > Median 36 48,6% 23,0 (11;*) 11,6 - 34,4 39,0%  
  1. Median survival shown in months; n.r.: not reached; CI: confidence interval; 3-Y-S: 3-Year-Survival; ; IQR: inter quartile range (1st quartile; 3rd quartile (* 3rd quartile not reached)).