Resveratrol inhibited the invasive ability of the orthotopic transplantation tumor. (A) Resveratrol with a dose of 0, 50, 100, 150 mg/kg was interfered in distinct groups for the orthotopic transplantation tumor mice via intragastric administration every day for 3 weeks. After 42 days, HE staining was performed to check the numbers of metastatic lesions. (B) The numbers of the lung metastases and hepatic metastases were counted, **P < 0.01, compared with group without treatment of resveratrol. (C) The finally excised primary tumors were weighed, **P < 0.01, compared with group without treatment of resveratrol.