TY - JOUR AU - Ji, Qing AU - Liu, Xuan AU - Han, Zhifen AU - Zhou, Lihong AU - Sui, Hua AU - Yan, Linlin AU - Jiang, Haili AU - Ren, Jianlin AU - Cai, Jianfeng AU - Li, Qi PY - 2015 DA - 2015/03/05 TI - Resveratrol suppresses epithelial-to-mesenchymal transition in colorectal cancer through TGF-β1/Smads signaling pathway mediated Snail/E-cadherin expression JO - BMC Cancer SP - 97 VL - 15 IS - 1 AB - Resveratrol extracted from grape has been an ideal alternative drug in the therapy of different cancers including colorectal cancer (CRC). Since the underlying mechanisms of resveratrol on the invasion and metastasis of CRC have not been fully elucidated, and epithelial-to-mesenchymal transition (EMT) is a key process associated with the progression of CRC, here we aimed to investigate the potential mechanism of resveratrol on the inhibition of TGF-β1-induced EMT in CRC LoVo cells. SN - 1471-2407 UR - https://doi.org/10.1186/s12885-015-1119-y DO - 10.1186/s12885-015-1119-y ID - Ji2015 ER -