Nuclear expression of p65 (RelA) in patients receiving post-operative radiotherapy for locally advanced squamous cell carcinoma of the head and neck

Table 4 Univariate analysis of loco-regional control

	At 1 year (%)	At 2 years (%)	At 3 years (%)	P
P65 expression
Negative	88	76	72
Positive	43	n.a.	n.a.	<0.001
Age
≤ 60 years	83	70	67
≥ 61 years	90	79	75	0.23
Gender
Female	91	78	78
Male	84	71	67	0.31
Karnofsky performance score
≤ 70	83	69	64
≥ 80	88	77	74	0.19
Hemoglobin level pre-RT
< 12 g/dl	79	60	60
≥ 12 g/dl	89	78	73	0.037
Tumor Site
Oropharynx	91	83	79
Oral Cavity/Floor of mouth	74	46	46
Hypopharynx	82	71	71
Larynx	87	77	69	0.050
Histologic grade
G1-2	91	78	74
G3	82	70	67	0.24
HPV status
Negative	84	69	65
Positive	94	94	94	0.041
T-classification
T1-T2	92	83	77
T3-T4	80	64	64	0.007
N-classification
N0-N2a	90	82	82
N2b-N3	83	68	63	0.040
AJCC stage
Stage III	91	82	82
Stage IV	83	68	63	0.042
Extent of resection
Complete	88	75	71
Incomplete	78	67	67	0.46
Chemotherapy
No	87	77	70
Yes	85	69	69	0.99

ISSN: 1471-2407