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Table 3 Univariate analysis of metastases-free survival

From: Nuclear expression of p65 (RelA) in patients receiving post-operative radiotherapy for locally advanced squamous cell carcinoma of the head and neck

  At 1 year (%) At 2 years (%) At 3 years (%) P
P65 expression
Negative 87 79 76  
Positive 86 n.a. n.a. 0.29
Age
  ≤ 60 years 89 77 74  
  ≥ 61 years 85 82 76 0.90
Gender
Female 91 84 77  
Male 86 77 75 0.41
Karnofsky performance score
  ≤ 70 82 72 63  
  ≥ 80 91 83 81 0.049
Hemoglobin level pre-RT
  < 12 g/dl 83 75 75  
  ≥ 12 g/dl 89 80 75 0.79
Tumor Site
Oropharynx 93 87 81  
Oral Cavity/Floor of mouth 82 70 70  
Hypopharynx 72 55 55  
Larynx 91 87 79 0.036
Histologic grade
G1-2 86 78 73  
G3 88 79 76 0.90
HPV status
Negative 87 76 72  
Positive 95 95 95 0.09
T-classification
T1-T2 95 88 85  
T3-T4 80 71 65 0.013
N-classification
N0-N2a 96 90 90  
N2b-N3 82 72 67 0.004
AJCC stage
Stage III 95 89 89  
Stage IV 83 73 68 0.011
Extent of resection
Complete 90 84 80  
Incomplete 74 57 57 0.002
Chemotherapy
No 88 86 82  
Yes 86 71 68 0.16
  1. n.a. = not available; significant p-values are given in bold.