At 1 year (%) | At 2 years (%) | At 3 years (%) | P | |
---|---|---|---|---|
P65 expression | ||||
Negative | 90 | 71 | 68 | |
Positive | 71 | n.a. | n.a. | <0.001 |
Age | ||||
≤ 60 years | 89 | 68 | 66 | |
≥ 61 years | 89 | 70 | 66 | 0.92 |
Gender | ||||
Female | 91 | 84 | 78 | |
Male | 88 | 64 | 62 | 0.19 |
Karnofsky performance score | ||||
≤ 70 | 88 | 57 | 49 | |
≥ 80 | 90 | 76 | 76 | 0.012 |
Hemoglobin level pre-RT | ||||
< 12 g/dl | 83 | 46 | 46 | |
≥ 12 g/dl | 92 | 78 | 74 | 0.002 |
Tumor Site | ||||
Oropharynx | 93 | 76 | 72 | |
Oral Cavity/Floor of mouth | 90 | 53 | 47 | |
Hypopharynx | 77 | 56 | 56 | |
Larynx | 89 | 75 | 75 | 0.35 |
Histologic grade | ||||
G1-2 | 95 | 73 | 69 | |
G3 | 85 | 65 | 63 | 0.26 |
HPV status | ||||
Negative | 87 | 65 | 62 | |
Positive | 100 | 93 | 93 | 0.023 |
T-classification | ||||
T1-T2 | 94 | 82 | 77 | |
T3-T4 | 84 | 56 | 56 | 0.009 |
N-classification | ||||
N0-N2a | 96 | 81 | 81 | |
N2b-N3 | 85 | 61 | 57 | 0.024 |
AJCC stage | ||||
Stage III | 98 | 82 | 82 | |
Stage IV | 85 | 62 | 58 | 0.025 |
Extent of resection | ||||
Complete | 91 | 73 | 70 | |
Incomplete | 82 | 50 | 50 | 0.017 |
Chemotherapy | ||||
No | 88 | 69 | 67 | |
Yes | 90 | 68 | 65 | 0.99 |