| |
At 1 year (%)
|
At 2 years (%)
|
At 3 years (%)
|
P
|
|---|
|
P65 expression
|
|
Negative
|
90
|
71
|
68
| |
|
Positive
|
71
|
n.a.
|
n.a.
|
<0.001
|
|
Age
|
|
≤ 60 years
|
89
|
68
|
66
| |
|
≥ 61 years
|
89
|
70
|
66
|
0.92
|
|
Gender
|
|
Female
|
91
|
84
|
78
| |
|
Male
|
88
|
64
|
62
|
0.19
|
|
Karnofsky performance score
|
|
≤ 70
|
88
|
57
|
49
| |
|
≥ 80
|
90
|
76
|
76
|
0.012
|
|
Hemoglobin level pre-RT
|
|
< 12 g/dl
|
83
|
46
|
46
| |
|
≥ 12 g/dl
|
92
|
78
|
74
|
0.002
|
|
Tumor Site
|
|
Oropharynx
|
93
|
76
|
72
| |
|
Oral Cavity/Floor of mouth
|
90
|
53
|
47
| |
|
Hypopharynx
|
77
|
56
|
56
| |
|
Larynx
|
89
|
75
|
75
|
0.35
|
|
Histologic grade
|
|
G1-2
|
95
|
73
|
69
| |
|
G3
|
85
|
65
|
63
|
0.26
|
|
HPV status
|
|
Negative
|
87
|
65
|
62
| |
|
Positive
|
100
|
93
|
93
|
0.023
|
|
T-classification
|
|
T1-T2
|
94
|
82
|
77
| |
|
T3-T4
|
84
|
56
|
56
|
0.009
|
|
N-classification
|
|
N0-N2a
|
96
|
81
|
81
| |
|
N2b-N3
|
85
|
61
|
57
|
0.024
|
|
AJCC stage
|
|
Stage III
|
98
|
82
|
82
| |
|
Stage IV
|
85
|
62
|
58
|
0.025
|
|
Extent of resection
|
|
Complete
|
91
|
73
|
70
| |
|
Incomplete
|
82
|
50
|
50
|
0.017
|
|
Chemotherapy
|
|
No
|
88
|
69
|
67
| |
|
Yes
|
90
|
68
|
65
|
0.99
|
- n.a. = not available; significant p-values are given in bold.
