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Table 2 Univariate analysis of overall survival

From: Nuclear expression of p65 (RelA) in patients receiving post-operative radiotherapy for locally advanced squamous cell carcinoma of the head and neck

  At 1 year (%) At 2 years (%) At 3 years (%) P
P65 expression
Negative 90 71 68  
Positive 71 n.a. n.a. <0.001
Age
  ≤ 60 years 89 68 66  
  ≥ 61 years 89 70 66 0.92
Gender
Female 91 84 78  
Male 88 64 62 0.19
Karnofsky performance score
  ≤ 70 88 57 49  
  ≥ 80 90 76 76 0.012
Hemoglobin level pre-RT
  < 12 g/dl 83 46 46  
  ≥ 12 g/dl 92 78 74 0.002
Tumor Site
Oropharynx 93 76 72  
Oral Cavity/Floor of mouth 90 53 47  
Hypopharynx 77 56 56  
Larynx 89 75 75 0.35
Histologic grade
G1-2 95 73 69  
G3 85 65 63 0.26
HPV status
Negative 87 65 62  
Positive 100 93 93 0.023
T-classification
T1-T2 94 82 77  
T3-T4 84 56 56 0.009
N-classification
N0-N2a 96 81 81  
N2b-N3 85 61 57 0.024
AJCC stage
Stage III 98 82 82  
Stage IV 85 62 58 0.025
Extent of resection
Complete 91 73 70  
Incomplete 82 50 50 0.017
Chemotherapy
No 88 69 67  
Yes 90 68 65 0.99
  1. n.a. = not available; significant p-values are given in bold.