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Table 2 Univariate analysis of overall survival

From: Nuclear expression of p65 (RelA) in patients receiving post-operative radiotherapy for locally advanced squamous cell carcinoma of the head and neck

 

At 1 year (%)

At 2 years (%)

At 3 years (%)

P

P65 expression

Negative

90

71

68

 

Positive

71

n.a.

n.a.

<0.001

Age

  ≤ 60 years

89

68

66

 

  ≥ 61 years

89

70

66

0.92

Gender

Female

91

84

78

 

Male

88

64

62

0.19

Karnofsky performance score

  ≤ 70

88

57

49

 

  ≥ 80

90

76

76

0.012

Hemoglobin level pre-RT

  < 12 g/dl

83

46

46

 

  ≥ 12 g/dl

92

78

74

0.002

Tumor Site

Oropharynx

93

76

72

 

Oral Cavity/Floor of mouth

90

53

47

 

Hypopharynx

77

56

56

 

Larynx

89

75

75

0.35

Histologic grade

G1-2

95

73

69

 

G3

85

65

63

0.26

HPV status

Negative

87

65

62

 

Positive

100

93

93

0.023

T-classification

T1-T2

94

82

77

 

T3-T4

84

56

56

0.009

N-classification

N0-N2a

96

81

81

 

N2b-N3

85

61

57

0.024

AJCC stage

Stage III

98

82

82

 

Stage IV

85

62

58

0.025

Extent of resection

Complete

91

73

70

 

Incomplete

82

50

50

0.017

Chemotherapy

No

88

69

67

 

Yes

90

68

65

0.99

  1. n.a. = not available; significant p-values are given in bold.