|  |  | NAT2 rapid acetylators | NAT2 slow/intermediate acetylators | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Population | Risk factors | Variables | Controls | Cases | OR (95% CI)a | P-value | Controls | Cases | OR (95% CI)a | P-value |
Black | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | Tobacco smoking | Never smokers | 49 | 39 | 1 (Ref) |  | 206 | 132 | 1 (Ref) |  |
 |  | Smokersb | 38 | 51 | 2.58 (0.80-8.25) | 0.111 | 180 | 220 | 2.76 (1.69-4.52) | <0.0001 |
 | Tot cigarettes/day | 0 | 49 | 39 | 1 (Ref) |  | 206 | 132 | 1 (Ref) |  |
 |  | ≤9 | 23 | 31 | 2.23 (0.67-7.36) | 0.189 | 112 | 143 | 3.27 (1.93-5.54) | <0.0001 |
 |  | ≥10 | 13 | 19 | 3.79 (0.92-15.7) | 0.066 | 58 | 72 | 2.49 (1.34-4.62) | 0.004 |
 | Alcohol drinking | Non-drinkers | 34 | 39 | 1 (Ref) |  | 164 | 127 | 1 (Ref) |  |
 |  | Drinkersc | 53 | 51 | 0.94 (0.34-2.62) | 0.903 | 221 | 224 | 0.91 (0.59-1.41) | 0.675 |
 | Red meat intaked | 3 times/week or less | − | 55 |  |  | − | 198 | 1 (Ref) |  |
 |  | Daily or almost daily | − | 5 |  |  | − | 31 | 1.67 (0.61-4.58) | 0.316 |
 | White meat intaked | 3 times/week or less | − | 33 |  |  | − | 113 | 1 (Ref) |  |
 |  | Daily or almost daily | − | 27 |  |  | − | 117 | 1.28 (0.72-2.29) | 0.397 |
Mixed Ancestry | Â | Â | Â | Â | Â | Â | Â | Â | Â | |
 | Tobacco smoking | Never smokers | 8 | 2 | 1 (Ref) |  | 54 | 12 | 1 (Ref) |  |
 |  | Smokersb | 41 | 53 | − | − | 185 | 191 | − | − |
 | Tot cigarettes/day | 0 | 8 | 2 | 1 (Ref) |  | 54 | 12 | 1 (Ref) |  |
 |  | ≤9 | 22 | 25 | − | − | 96 | 58 | − | − |
 |  | ≥10 | 16 | 27 | − | − | 74 | 129 | − | − |
 | Alcohol drinking | Non-drinkers | 15 | 9 | 1 (Ref) |  | 100 | 41 | 1 (Ref) |  |
 |  | Drinkersc | 34 | 47 | 2.43 (0.65-9.15) | 0.188 | 138 | 162 | 2.77 (1.38-5.58) | 0.004 |
 | Red meat intaked | 3 times/week or less | − | 31 |  |  | − | 75 | 1 (Ref) |  |
 |  | Daily or almost daily | − | 5 |  |  | − | 43 | 3.55 (1.29-9.82) | 0.019 |
 | White meat intaked | 3 times/week or less | − | 20 |  |  | − | 51 | 1 (Ref) |  |
 |  | Daily or almost daily | − | 16 |  |  | − | 66 | 1.80 (0.81-4.02) | 0.149 |