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Table 7 Major pathways of BRmet50 and PMID18271932Sig33

From: Evaluation of public cancer datasets and signatures identifies TP53 mutant signatures with robust prognostic and predictive value

Pathways

BRmet50

PMID18271932Sig33

Cell cycle: mitotic roles of polo-like kinase

KIF23,PRC1,CCNB2

KIF23,PTTG1,PRC1,CCNB2,PKMYT1,PLK1

Cell cycle: G2/M checkpoint regulation

CCNB2

CCNB2,PKMYT1,PLK1

Cell cycle: control of chromosomal replication

CDC45,CDT1

CDC45

Cell cycle: regulation

CCNB2

CCNB2

Cell cycle: checkpoint control

RFC4

PLK1

DNA damage: 14-3-3σ signaling

CCNB2

CCNB2

DNA damage repair: ATM signaling

RAD51,CCNB2

CCNB2

DNA damage response: BRCA1 pathway

RAD51,RFC4

PLK1

DNA damage response: salvage pathways of pyrimidine ribonucleotides

NEK2

PLK1

Protein ubiquitination

UBE2S,UBE2C

UBE2C