Table 13 Prediction metrics for studies reporting hazard ratios

Jeong et al. [22]

OS

YA subgroup vs. YI subgroup

0.5

0.31−0.82

0.005

Roque et al. [24]

OS

High vs. low TUBB3 staining

3.66

1.11−12.05

707 days vs. not reached

0.03

Kang et al. [31]

OS

High vs. low score

0.33

0.13−0.86

1.8 years vs. 2.9 years

<0.001

Skirnisdottir and Seidal [35]

Recurrence

p53 -ve vs. +ve

4.12

1.41−12.03

0.009

Schlumbrecht et al. [40]

RFS

EIG121 high vs. low

1.13

1.02−1.26

0.021

Yoshihara et al. [43]

PFS

High vs. low score

1.64

1.27−2.13

0.0001

Denkert et al. [45]

OS

Low vs. high score

1.7

1.1−2.6

0.021

Crijns et. al [47]

OS

1.94

1.19−3.16

0.008

Netinatsunthorn et al. [51]

RFS

Yes vs. no WT1 staining

3.36

1.60−7.03

0.0017

Spentzos et al. [54]

OS

Resistant vs. sensitive

3.9

1.3−11.4

41 months vs. not reached

<0.001^†

Raspollini et al. [56]

OS

No vs. yes COX-2 staining

0.23

0.06−0.77

0.017

Spentzos et al. [58]

OS

High vs. low score

4.6

2.0−10.7

30 months vs. not reached

0.0001