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Table 13 Prediction metrics for studies reporting hazard ratios

From: Prediction of resistance to chemotherapy in ovarian cancer: a systematic review

Study Prediction Classes HR 95% CI Median survival P value
Jeong et al. [22] OS YA subgroup vs. YI subgroup 0.5 0.31−0.82   0.005
Roque et al. [24] OS High vs. low TUBB3 staining 3.66 1.11−12.05 707 days vs. not reached 0.03
Kang et al. [31] OS High vs. low score 0.33 0.13−0.86 1.8 years vs. 2.9 years <0.001
Skirnisdottir and Seidal [35] Recurrence p53 -ve vs. +ve 4.12 1.41−12.03   0.009
Schlumbrecht et al. [40] RFS EIG121 high vs. low 1.13 1.02−1.26   0.021
Yoshihara et al. [43] PFS High vs. low score 1.64 1.27−2.13   0.0001
Denkert et al. [45] OS Low vs. high score 1.7 1.1−2.6   0.021
Crijns et. al [47] OS   1.94 1.19−3.16   0.008
Netinatsunthorn et al. [51] RFS Yes vs. no WT1 staining 3.36 1.60−7.03   0.0017
Spentzos et al. [54] OS Resistant vs. sensitive 3.9 1.3−11.4 41 months vs. not reached <0.001
Raspollini et al. [56] OS No vs. yes COX-2 staining 0.23 0.06−0.77   0.017
Spentzos et al. [58] OS High vs. low score 4.6 2.0−10.7 30 months vs. not reached 0.0001
  1. Calculated value.
  2. HR: Hazard Ratio.
  3. OS: Overall Survival.
  4. RFS: Relapse Free Survival.
  5. PFS: Progression Free Survival.
  6. CI: Confidence Interval.