Table 12 Prediction metrics for studies reporting sensitivity and specificity

Li et al. [3]

Chemoresistance

0.96^*

0.23^*

1.24

0.18

\(\frac {22}{44}\)

\(\frac {22}{44}\)

0.55

0.15

Obermayr et al. [27]

RFS

0.22^*

0.85^*

1.47

0.92

\(\frac {46}{216}\)

\(\frac {170}{216}\)

0.28

0.77

Ferriss et al. [33]

Chemoresponse

0.94^*

0.29^*

1.33

0.20

\(\frac {85}{119}\)

\(\frac {34}{119}\)

0.77

0.07

Sabatier et al. [37]

Prognosis

0.62^*

0.62^*

1.64

0.62

\(\frac {194}{366}\)

\(\frac {172}{366}\)

0.65

0.35

Yoshihara et al. [43]

PFS

0.64^*

0.69^*

2.06

0.52

\(\frac {45}{87}\)

\(\frac {39}{87}\)

0.69

0.30

Williams et al. [44]

Prognosis

0.77^*

0.56^*

1.75

0.41

\(\frac {97}{143}\)

\(\frac {46}{143}\)

0.79

0.16

Gevaert et al. [49]

Chemoresistance

0.67^*

0.40^*

1.12

0.82

\(\frac {15}{45}\)

\(\frac {30}{45}\)

0.36

0.62

Helleman et al. [53]

Chemoresistance

0.89^*

0.56^*

2.02

0.20

\(\frac {9}{72}\)

\(\frac {63}{72}\)

0.22

0.58

De Smet et al. [52]

Chemoresistance

0.71^†

0.83^†

4.29

0.34

\(\frac {6}{13}\)

\(\frac {7}{13}\)

0.79

0.29

Raspollini et al. [56]

Prognosis

0.79^†

0.46^†

1.45

0.47

\(\frac {28}{52}\)

\(\frac {24}{52}\)

0.63

0.29

Hartmann et al. [57]

Prognosis

0.86^*

0.86^*

6.14

0.16

\(\frac {21}{28}\)

\(\frac {7}{28}\)

0.95

0.05

Selvanayagam et al. [59]

Chemoresistance

1.00^†

1.00^†

∞

0.00

\(\frac {4}{8}\)

\(\frac {4}{8}\)

1.00

0.00

Kamazawa et al. [61]

Chemoresponse

1.00^*

0.83^†

6.00

0.00

\(\frac {21}{27}\)

\(\frac {5}{27}\)

0.95

0.00