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Table 12 Prediction metrics for studies reporting sensitivity and specificity

From: Prediction of resistance to chemotherapy in ovarian cancer: a systematic review

Study Prediction Sensitivity Specificity LR+ve LR-ve P(C+) P(C−) P(C+|T+) P(C+|T−)
Li et al. [3] Chemoresistance 0.96* 0.23* 1.24 0.18 \(\frac {22}{44}\) \(\frac {22}{44}\) 0.55 0.15
Obermayr et al. [27] RFS 0.22* 0.85* 1.47 0.92 \(\frac {46}{216}\) \(\frac {170}{216}\) 0.28 0.77
Ferriss et al. [33] Chemoresponse 0.94* 0.29* 1.33 0.20 \(\frac {85}{119}\) \(\frac {34}{119}\) 0.77 0.07
Sabatier et al. [37] Prognosis 0.62* 0.62* 1.64 0.62 \(\frac {194}{366}\) \(\frac {172}{366}\) 0.65 0.35
Yoshihara et al. [43] PFS 0.64* 0.69* 2.06 0.52 \(\frac {45}{87}\) \(\frac {39}{87}\) 0.69 0.30
Williams et al. [44] Prognosis 0.77* 0.56* 1.75 0.41 \(\frac {97}{143}\) \(\frac {46}{143}\) 0.79 0.16
Gevaert et al. [49] Chemoresistance 0.67* 0.40* 1.12 0.82 \(\frac {15}{45}\) \(\frac {30}{45}\) 0.36 0.62
Helleman et al. [53] Chemoresistance 0.89* 0.56* 2.02 0.20 \(\frac {9}{72}\) \(\frac {63}{72}\) 0.22 0.58
De Smet et al. [52] Chemoresistance 0.71 0.83 4.29 0.34 \(\frac {6}{13}\) \(\frac {7}{13}\) 0.79 0.29
Raspollini et al. [56] Prognosis 0.79 0.46 1.45 0.47 \(\frac {28}{52}\) \(\frac {24}{52}\) 0.63 0.29
Hartmann et al. [57] Prognosis 0.86* 0.86* 6.14 0.16 \(\frac {21}{28}\) \(\frac {7}{28}\) 0.95 0.05
Selvanayagam et al. [59] Chemoresistance 1.00 1.00 0.00 \(\frac {4}{8}\) \(\frac {4}{8}\) 1.00 0.00
Kamazawa et al. [61] Chemoresponse 1.00* 0.83 6.00 0.00 \(\frac {21}{27}\) \(\frac {5}{27}\) 0.95 0.00
  1. *Value stated in reference.
  2. Value calculated.
  3. C: condition presence.
  4. T: test result.
  5. RFS: Relapse Free Survival.
  6. PFS: Progression Free Survival.