Table 5 Comparison of the diagnostic performance of serum fibulin-4, CA-125, CA19-9, fibulin-4 + CA-125, fibulin-4 + CA19-9, CA-125 + CA19-9 and fibulin-4 + CA-125 + CA19-9
From: Fibulin-4 is associated with tumor progression and a poor prognosis in ovarian carcinomas
Marker | Sensitivity (%) | Specificity (%) | Positive predictive value (%) | Negative predictive value (%) | Positive likelihood ratio | Negative likelihood ratio |
|---|---|---|---|---|---|---|
fibulin-4 | 75.0 | 84.0 | 88.2 | 67.7 | 4.69 | 0.30 |
CA-125 | 70.6 | 79.0 | 84.3 | 62.7 | 3.36 | 0.37 |
CA19-9 | 61.3 | 70.0 | 76.6 | 53.0 | 2.04 | 0.55 |
fibulin-4 + CA-125 | 68.8 | 92.0 | 93.2 | 64.8 | 8.59 | 0.34 |
fibulin-4 + CA19-9 | 60.6 | 90.0 | 90.6 | 58.8 | 6.06 | 0.44 |
CA-125 + CA19-9 | 56.3 | 88.0 | 88.2 | 55.7 | 4.69 | 0.50 |
fibulin-4 + CA-125 + CA19-9 | 52.5 | 98.0 | 97.7 | 56.3 | 26.25 | 0.48 |