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Table 4 SIR of site-specific cancer of the HIV-infection patients group in different gender and overall population

From: Risk of cancer among HIV-infected patients from a population-based nested case–control study: implications for cancer prevention

 

Men

Women

All

 

Cases of cancer

Cases of cancer

Cases of cancer

Cancer site

Observed

Expected

SIR (95% CI)

Observed

Expected

SIR (95% CI)

Observed

Expected

SIR (95% CI)

ENT (140–149)

10

4

3.15*** (1.38 ~ 7.20)

1

<0.5

N/A

11

4

2.77*** (1.28 ~ 5.98))

 Oral (140–146)

8

2.75

4.09*** (1.53 ~ 10.93)

1

<0.5

N/A

9

2.75

3.29*** (1.36 ~ 7.96)

 Non- Oral (147–149)

2

2.25

0.85 (0.27 ~ 6.72)

<0.5

<0.5

N/A

2

2.25

0.89 (0.19 ~ 4.12)

GI (150 ~ 159)

20

7

2.99*** (1.69 ~ 5.27)

10

5

1.96 (0.77 ~ 3.41)

30

12

2.54*** (1.60 ~ 4.06)

 Liver (155)

11

3

3.76*** (1.65 ~ 8.55)

2

1.5

1.15 (0.35 ~ 2.43)

13

4.5

3.75*** (1.76 ~ 7.99)

 Colorectal (153–154)

7

2.5

2.59* (1.06 ~ 6.72)

4

2.5

1.52 (0.48 ~ 4.82)

11

5

2.21* (1.06 ~ 4.63)

 Others (150–152,156-159)

5

1.75

2.91*** (1.92 ~ 9.19)

3

2.25

1.36 (0.75 ~ 3.01)

8

4

2.01 (0.86 ~ 4.70)

 Anus (154.2-154.8)

<0.5

<0.5

N/A

1

<0.5

N/A

1

<0.5

N/A

 Stomach (151)

2

0.75

2.71 (0.45 ~ 16.24)

1

<0.5

N/A

3

1

3.07 (0.69 ~ 13.73)

Respiratory & intrathoracic (160–165)

12

3.25

3.28*** (1.53 ~ 7.03)

4

1

4.53*** (1.21 ~ 14.69)

16

3.75

4.31*** (2.13 ~ 8.75)

 Lung (162)

9

3.25

2.83*** (1.21 ~ 6.64)

4

0.5

6.13*** (1.87 ~ 28.69)

13

3.75

3.49*** (1.66 ~ 7.37)

 Non Lung (160–161, 163–165)

4

<0.5

N/A

1

<0.5

N/A

5

<0.5

N/A

Bone,connective tissue (170–176)

15

<0.5

N/A

7

2.75

3.26*** (1.59 ~ 11.46)

22

3

7.46*** (3.68 ~ 15.12)

 Breast (174–175)

1

<0.5

N/A

4

1.25

2.80*** (1.29 ~ 10.01)

5

1.25

4.01* (1.16 ~ 13.89)

 Skin & soft tissue (170–173)

2

<0.5

N/A-

4

1.5

8.44*** (1.54 ~ 46.32)

6

1.75

3.44* (1.15 ~ 10.26)

 Malignant melanoma of skin (172)

<0.5

<0.5

N/A

<0.5

<0.5

N/A

<0.5

<0.5

N/A

 Other skin & soft tissue (170, 171, 173)

2

<0.5

N/A

4

1.5

8.44*** (1.54 ~ 46.32)

6

1.75

3.44* (1.15 ~ 10.26)

 Kaposi (176)

12

<0.5

N/A

<0.5

<0.5

N/A

12

<0.5

N/A

 Bone (170)

<0.5

<0.5

N/A

<0.5

<0.5

N/A

<0.5

<0.5

N/A

GU (180–189)

7

2.5

2.57*** (1.29 ~ 9.88)

9

3

3.71*** (1.84 ~ 12.59)

16

5.5

2.94*** (1.54 ~ 5.61)

 Kidney & bladder (188–189)

4

0.5

8.15*** (1.49 ~ 44.58)

2

0.75

2.15 (0.87 ~ 8.65)

6

1.25

4.82*** (1.47 ~ 15.83)

 Cervical (180)

<0.5

<0.5

N/A

4

1

4.01* (1.0 ~ 16.06)

4

1

4.01* (1.0 ~ 16.06)

 Others (179,181-187)

4

1.25

2.71 (0.76 ~ 9.64)

5

2.5

2.75*** (1.21 ~ 6.25)

9

3.75

2.41* (1.05 ~ 5.53)

Lymphoma (200–203)

12

0.75

12.22*** (3.08 ~ 36.12)

3

0.89

3.38(0.63 ~ 8.28)

15

0.75

20.26*** (5.86 ~ 70.10)

 Non Hodgkin lymphoma (200, 202.0-202.2, 202.8-202.9)

10

0.5

21.65*** (5.65 ~ 88.75)

3

0.77

3.90(0.73 ~ 9.55)

13

0.5

25.73*** (6.83 ~ 90.85)

Leukemia (204–208)

1

1

1.00 (0.10 ~ 8.96)

<0.5

<0.5

N/A

1

1

1.00 (0.10 ~ 8.96)

CNS (190–192)

2

<0.5

N/A

3

<0.5

N/A

5

<0.5

N/A

Thyroid (193)

<0.5

<0.5

N/A

2

<0.5

N/A

2

1

2.01 (0.37 ~ 10.94)

Others (194–199)

6

4

2.05 (0.76 ~ 3.99)

6

3.25

1.76 (0.89 ~ 6.16)

12

7.25

1.66 (0.85 ~ 3.37)

  1. SIR: standardized incidence ratios.
  2. ENT: ear-nasal cavity-throat.
  3. CNS: central nervous system.
  4. GI: gastroenteral.
  5. GU: genitouro.
  6. *P < 0.05, ***P < 0.001.
  7. N/A: no calculation of SIR due to case number or expected number less than 0.5.