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Table 3 Cox regression analysis for various potential prognostic factors in recurrence-free survival

From: Clinically significant association between the maximum standardized uptake value on 18F-FDG PET and expression of phosphorylated Akt and S6 kinase for prediction of the biological characteristics of renal cell cancer

    Recurrence-free survival in cN0M0 cases
Variable Unfavorable/favorable characteristics No. of Patients Analysis Relative risk 95% confidential interval P value
p-SUVmax* high/low 26/26 Univariate (U) 14.361 4.283 - 64.472 0.00940
Multivariate (M) 1.714 0.021 - 142.351 0.64270
pAkt (Ser473) high/low 26/26 U 5.895 1.688 - 50.514 0.03910
M 2.374 0.062 - 367.647 0.78520
pAkt (Thr308) high/low 25/27 U 5.321 1.621 - 45.612 0.04810
  2.157 0.069 - 397.026 0.79130
pS6 high/low 26/26 U 3.994 0.466 - 34.272 0.12190
M    
Grade 4/3/2/1 2/13/28/9 U 11.397 3.320 - 33.119 0.00007
M 31.171 1.836 - 529.228 0.01730
pT 4,3/2,1 13/39 U 7.807 1.920 - 31.753 0.00410
M 5.151 0.187 - 151.279 0.15370
v 1/0 24/28 U 4.941 1.016 - 24.035 0.04780
M 2.355 0.156 - 35.559 0.53630
cell type sarcomatoid/non-cc/cc* 3/9/40 U 7.051 2.634 - 18.876 0.00010
M 1.029 0.091 - 11.577 0.78180
  1. p-SUVmax*: SUVmax value in the primary tumor.
  2. sarcomatoid/non-cc/cc*: sarcomatoid differentiation/non-clear cell RCC/clear cell RCC.