Table 2 Relationship between SUVmax and pAkt/pS6K protein densitometry results and pathological parameters

Tissue

tumor

n=77

6.97 ± 5.96

n=77

3.91 ± 3.01

0.000001

2.83 ± 2.13

0.000009

2.43 ± 1.58

0.000021

non-tumor

n=77

1.00

1.00

1.00

Histological differentiation (Fuhrman grade)

G1

n=9

2.72 ± 0.66

0.000073

n=9

1.54 ± 0.57

0.000041

1.21 ± 0.36

0.000089

1.13 ± 0.15

0.000079

G2

n=32

3.90 ± 2.33

n=32

2.57 ± 2.03

2.03 ± 1.57

1.86 ± 1.08

G3

n=29

8.80 ± 3.79

n=29

5.16 ± 2.73

3.46 ± 1.85

2.81 ± 1.23

G4

n=7

18.67 ± 10.23

n=7

8.09 ± 3.49

6.00 ± 2.71

5.19 ± 2.07

pT stage

pT1-2

n=43

3.77 ± 2.02

0.000019

n=43

2.43 ± 1.74

0.000029

1.93 ± 1.49

0.000083

1.75 ± 0.95

0.000100

pT3-4

n=34

10.91 ± 6.82

n=34

5.83 ± 3.24

4.00 ± 2.27

3.31 ± 1.79

Microscopic vascular invasion

v0

n=28

3.33 ± 1.46

0.000061

n=28

2.08 ± 1.22

0.000100

1.67 ± 1.14

0.000200

1.60 ± 0.78

0.001000

v1

n=49

9.01 ± 6.55

n=49

4.97 ± 3.23

3.50 ± 2.28

2.91 ± 1.72

pN stage

N0

n=62

5.58 ± 5.80

0.000053

n=62

3.13 ± 2.54

0.000076

2.41 ± 2.00

0.000200

2.04 ± 1.31

0.000092

N1-2

n=15

12.38 ± 2.59

n=15

7.38 ± 2.45

4.68 ± 1.64

4.14 ± 1.56

Metastasis (cM stage)

M0

n=52

4.56 ± 3.59

0.000029

n=52

2.55 ± 2.03

0.000043

2.07 ± 1.69

0.000085

1.81 ± 1.52

0.000078

M1

n=25

12.10 ± 6.78

n=25

7.04 ± 2.53

4.57 ± 2.03

3.85 ± 1.16

cell histology

clear cell carcinoma

n=57

4.94 ± 3.15

0.000069

n=57

3.16 ± 2.44

0.000500

2.28 ± 1.68

0.000300

2.03 ± 1.19

0.001300

non-clear cell carcinoma

n=11

9.44 ± 5.04

n=11

4.43 ± 3.36

3.21 ± 2.11

3.41 ± 2.24

Sarcomatoid*

n=9

16.54 ± 9.37

n=9

8.56 ± 1.88

6.17 ± 2.02

3.95 ± 1.59