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Table 2 Meta-analysis of the association between HPV 16 and esophageal cancer by different variables

From: The association between human papillomavirus 16 and esophageal cancer in Chinese population: a meta-analysis

Variable Number of studies OR (95% CI) Heterogeneity
Pfor Q test I2(%)
Region     
North 4 8.15 (4.79, 13.86) 0.084 54.9
Northwest 4 4.36 (2.95, 6.44) 0.357 7.2
South 2 6.50 (3.12, 13.55) 0.209 36.5
Year     
2005-2009 4 6.65 (4.07, 10.86) 0.384 1.60
2010-2014 6 6.03 (3.72, 9.77) 0.004 70.7
Specimen (1)     
PE 7 5.48 (3.88, 7.52) 0.169 34.0
FF 3 8.48 (3.99, 9.41) 0.072 61.9
HPV detection method     
L1 5 7.87 (4.71, 13.16) 0.052 57.3
E6 5 4.68 (3.40, 6.44 ) 0.473 0.00
  1. (1)FF: Fresh-Frozen; PE: Paraffin-Embedded.