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Table 2 Meta-analysis of the association between HPV 16 and esophageal cancer by different variables

From: The association between human papillomavirus 16 and esophageal cancer in Chinese population: a meta-analysis

Variable

Number of studies

OR (95% CI)

Heterogeneity

Pfor Q test

I2(%)

Region

    

North

4

8.15 (4.79, 13.86)

0.084

54.9

Northwest

4

4.36 (2.95, 6.44)

0.357

7.2

South

2

6.50 (3.12, 13.55)

0.209

36.5

Year

    

2005-2009

4

6.65 (4.07, 10.86)

0.384

1.60

2010-2014

6

6.03 (3.72, 9.77)

0.004

70.7

Specimen (1)

    

PE

7

5.48 (3.88, 7.52)

0.169

34.0

FF

3

8.48 (3.99, 9.41)

0.072

61.9

HPV detection method

    

L1

5

7.87 (4.71, 13.16)

0.052

57.3

E6

5

4.68 (3.40, 6.44 )

0.473

0.00

  1. (1)FF: Fresh-Frozen; PE: Paraffin-Embedded.