Table 1 Tumor area as measured by number of pixels (x10 ⁷ ) for A431 xenografts, and ectopic or orthotopic MCF-7 xenografts taken on Day 0 (untreated), 2, 4, 8, or 12 following a single dose of paclitaxel (25 mg/kg, i.p.), doxorubicin (DOX 8 mg/kg, i.v.), or 5-FU (100 mg/kg, i.p.)

0

1.18 (0.27)

2.29 (0.25)

2.29 (0.25)

4.79 (0.65)

7.40 (4.60)

4.79 (0.65)

7.40 (4.60)

4.79 (0.65)

7.40 (4.60)

2

______

2.43 (0.38)

1.96 (0.19)

______

3.25 (1.41)

6.99 (0.91)

2.53 (0.55)

7.27 (1.16)

5.34 (1.24)

4

1.67 (0.16)

2.70 (0.49)

2.71 (0.49)

3.94 (0.61)

5.04 (1.41)

4.86 (1.33)

3.29 (---)

1.27 (0.53)*

4.49 (2.08)

8

0.99 (0.15)

2.42 (0.36)

1.92 (0.32)

3.78 (0.47)

5.20 (0.80)

3.39 (0.63)

4.06 (1.35)

5.11 (1.17)

5.85 (0.76)

12

0.47 (0.06)*

2.11 (0.47)

1.27 (0.37)

4.57 (0.33)

2.05 (0.82)

3.17 (0.65)

______

3.34 (0.85)

7.48 (0.83)