Prognostic relevance of positive urine markers in patients with negative cystoscopy during surveillance of bladder cancer

Table 4 Prediction of recurrence and progression occurring between month 12-24 after urine sampling

Test	Result	n	Rate of tumor recurrence in % (between month 12-24)	Hazard ratio	p-value	Rate of tumor progression in % (between month 12-24)	Hazard ratio	p-value
Cytology	-	68	14.7	2.89 (1.1-8.3)	.04	2.9	5.7 (1.1-43.4)	.04
Cytology	+	27	33.3	2.89 (1.1-8.3)	.04	14.8	5.7 (1.1-43.4)	.04
FISH	-	63	14.3	2.72 (1.0-7.8)	.05	3.2	4.35 (0.8-32.8)	.08
FISH	+	32	31.3	2.72 (1.0-7.8)	.05	12.5	4.35 (0.8-32.8)	.08
uCyt+	-	60	13.3	2.9 (1.1-8.6)	.03	3.3	3.7 (0.7-28.1	.12
uCyt+	+	35	31.4	2.9 (1.1-8.6)	.03	11.4	3.7 (0.7-28.1	.12
NMP22	-	45	11.1	3.1 (1.1-10.4	.03	6.7	1.11 (0.2-6.3)	.89
NMP22	+	50	28.0	3.1 (1.1-10.4	.03	6.0	1.11 (0.2-6.3)	.89

FISH = Fluorescence in situ hybridization, uCyt + = Immunocytology, NMP22 = Nuclear matrix protein 22.

ISSN: 1471-2407