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Table 3 Prediction of progression by single urine markers in case of negative cystoscopy in the follow up of non muscle invasive bladder cancer

From: Prognostic relevance of positive urine markers in patients with negative cystoscopy during surveillance of bladder cancer

Test Result n Rate of tumor progression in % (12 months) Hazard ratio p-value Rate of tumor progression in % (24 months) Hazard ratio p-value
Cytology - 75 1.3 11.6 (1.7-226.1) .008 4.0 7.2 (2.0-34.2) <.001
+ 39 13.5 23.1
FISH - 72 1.4 9.72 (1.5-189.9) .01 4.2 6.2 (1.7-29.7) .004
+ 42 12.2 21.4
uCyt+ - 67 1.5 8.3 (1.3-161.0) .025 4.5 5.1 (1.4-23.8) .01
+ 66 11.1 19.2
NMP22 - 48 0 28×106
(2.04-n.a.)
.009 6.2 2.4 (0.7-11.1) .19
+ 66 9.2 13.6
  1. FISH = Fluorescence in situ hybridization, uCyt + = Immunocytology, NMP22 = Nuclear matrix protein 22.