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Table 2 Prediction of recurrence by single urine markers in case of negative cystoscopy in the follow up of non muscle invasive bladder cancer

From: Prognostic relevance of positive urine markers in patients with negative cystoscopy during surveillance of bladder cancer

Urine marker Result n Rate of tumor recurrence in % (after 12 months) Hazard ratio p-value Rate of tumor recurrence in % (after 24 months) Hazard ratio p-value
Cytology - 75 9.3 4.3 (1.6-12.7) .004 21.9 3.9 (1.75-9.2) <.001
+ 39 30.7 52.6
FISH - 72 12.5 2.2 (0.8-6.0) .12 25.0 3.3 (1.5-7.6) .01
+ 42 23.8 47.6
uCyt+ - 67 10.5 2.93 (1.2-8.0). .03 22.4 2.7 (1.2-6.2) .003
+ 66 25.5 43.8
NMP22 - 48 6.3 4.79 (1.47-21.6) .007 16.7 4.2 (1.7-10.8) .001
+ 66 24.4 43.8
  1. FISH = Fluorescence in situ hybridization, uCyt + = Immunocytology, NMP22 = Nuclear matrix protein 22.