Table 6 Common significant pathways associated with up-regulated and down-regulated genes of putative CSCs

Up-regulated

hsa00982

Drug metabolism

3.661

–

–

hsa02010

ABC transporters

3.041

–

–

hsa04010

MAPK signalling pathway

–

1.933

1.870

hsa04310

Wnt signalling pathway

1.063

1.025

-

hsa04514

Cell adhesion molecules (CAMs)

1.419

–

1.719

hsa04520

Adherens junction

1.390

–

–

hsa05200

Pathways in cancer

–

0.944

1.384

hsa05223

Non-small cell lung cancer

–

1.912

4.203

Down-regulated

hsa04115

p53 signalling pathway

3.935

2.589

2.660

hsa04210

Apoptosis

1.957

2.783

2.079

hsa04340

Hedgehog signalling pathway

1.737

–

–

hsa04512

ECM-receptor interaction

3.765

3.668

3.589

hsa05200

Pathways in cancer

2.225

1.946

1.960

hsa05222

Small cell lung cancer

2.027

2.096

2.392