Table 5 Analysis using Cox regression model for independent risk factors after R0 D2 gastrectomy (n = 550)

Independent significant risk factors

T3/4 (serosapositive)

0,003

2,35 (1,35 - 4,12)

Signet ring cell

0,004

3,88 (1,56 - 9,71)

Nodal positive

0,003

2,39 (1,34 - 4,26)

Grading 3/4

0,018

2,03 (1,13 - 3,65)

Non significant risk factors

Time period (I)

0,247

1,39 (0,69 - 2,81)

Age (<50y)

0,776

0,82 (1,65 - 0,41)

Sex (male)

0,399

1,25 (2,08 - 0,75)

Perioperative chemotherapy

0,392

0,68 (1,64 - 0,28)