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Table 2 Characteristics of treatment and response by histology

From: Metaplastic breast cancer: a comparison between the most common histologies with poor immunohistochemistry factors

  

MCBn(%)

TN-ILCn(%)

HG-IDCn(%)

TN-IDCn(%)

pvalue

 

Amount received

24

37

48

48

 

Ind CT

 

12 (50)

20 (54.1)

38 (79.2)

39 (81.3)

<0.003

Response

pPR

2 (16.7)

15 (75)

26 (65)

24 (61.5)

<0.001

 

pCR

3 (25.0)

2 (10.0)

12 (30)

11 (28.2)

 
 

Stable

1 (8.3)

1 (5)

0

2 (5.1)

 
 

Progression

6 (50)

2 (10)

2 (5)

2 (5.1)

 

Surgery

BCS

0

0

3 (6.3)

7 (14.6)

0.011

 

MRM

22 (91.7)

24 (64.9)

38 (79.2)

37 (77.1)

 
 

No

2 (8.3)

13 (35.1)

7 (14.6)

4 (8.3)

 

Adjuvancy

Received

14 (58.3)

26 (70.3)

37 (77.1)

29 (60.4)

0.245

 

CT

11 (45.8)

22 (59.5)

19 (39.6)

36 (75.0)

0.009

 

RT

14 (58.3)

22 (59.5)

23 (47.9)

27 (56.3)

0.705

Recurrence

No

15 (62.5)

13 (35.1)

28 (58.3)

29 (60.4)

0.094

 

Recurrence

3 (12.5)

12 (32.4)

18 (37.5)

16 (33.3)

 
 

Progression

6 (25)

12 (32.4)

2 (4.2)

3 (6.3)

 
  1. MCB: metaplastic carcinoma of the breast; TN-ILC: triple-negative invasive lobular carcinoma; HG-IDC: high-grade invasive ductal carcinoma; TN-IDC: triple-negative invasive ductal carcinoma; Ind CT: induction of chemotherapy; pPR: pathologic partial response; pCR: pathologic complete response; BCS: breast-conserving surgery; MRM: modified radical mastectomy; CT: adjuvant chemotherapy; RT: radiotherapy.