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Table 1 Patient characteristics and associations with CSF-1 expression

From: Increased expression of colony stimulating factor-1 is a predictor of poor prognosis in patients with clear-cell renal cell carcinoma

 

Training cohort

Validation cohort

Variable

Patients

CSF-1 expression

P

Patients

CSF-1 expression

P

 

Number

%

Low (n = 99)

High (n = 96)

 

Number

%

Low (n = 43)

High (n = 29)

 

Age (years)*

55.3

56.2

54.3

0.245

59.8

61.5

59.1

0.421

Gender

    

0.987

    

0.982

Male

137

70.3

70

67

 

51

70.8

31

20

 

Female

58

29.7

29

29

 

21

29.3

12

9

 

Tumor size (cm)*

4.7

4.4

4.9

0.194

5.2

4.8

5.8

0.106

TNM stage

    

0.091

    

0.077

I + II

134

68.7

74

60

 

56

77.8

37

19

 

III + IV

61

31.3

25

36

 

16

22.2

6

10

 

Fuhrman grade

    

0.001

    

0.007

1 + 2

122

62.6

74

48

 

49

68.1

35

14

 

3 + 4

73

37.4

25

48

 

23

31.9

8

15

 

Necrosis

    

0.013

    

0.039

Absent

150

76.9

84

66

 

55

76.4

37

18

 

Present

45

23.1

15

30

 

17

23.6

6

11

 

ECOG PS

          

0

160

82.1

80

80

0.785

59

81.9

36

23

0.869

≥1

35

17.9

19

16

 

13

18.1

7

6

 
  1. CSF-1 = Colony Stimulating Factor 1.
  2. ECOG-PS = Eastern Cooperative Oncology Group performance status.
  3. *Student’s t test and χ2 test for all the other analyses.
  4. The bold characters indicate that these P values are considered statistically significant.