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Table 2 Summary of tumor characteristics and treatment parameters

From: Gamma knife radiosurgery for elderly patients with brain metastases: evaluation of scoring systems that predict survival

Parameter No. (%)
Characteristics of systemic course
Number of patients 147
Sex  
 Female 39 (26.6%)
 Male 108 (73.4%)
Age  
 Median (range) 75.6 (70–86)
 70 - 75 80 (54.4%)
 >75 67 (45.6%)
Signs and symptoms  
 Mental status change 10 (6.8%)
 Dizziness 12 (8.2%)
 Motor/sensory deficit 40 (27.3%)
 Gait disturbance 1 (0.7%)
 Headache 27 (18.3%)
 Nausea & vomiting 2 (1.3%)
 Swallowing difficulty 2 (1.3%)
 Incidental detect 53 (36.1%)
Karnofsky Performance Status (KPS)  
 Median (range) 84 (40–100)
 ≤60 21 (14.2%)
 70-80 41 (28.0%)
 90≤ 85 (57.8%)
Primary tumor  
 Lung cancer 111 (75.5%)
 Rectal cancer 7 (4.7%)
 Colon cancer 6 (4.0%)
 Gastric cancer 3 (2.0%)
 Breast cancer 6 (4.0%)
 Cervix cancer 1 (0.6%)
 Gall bladder cancer 2 (1.2%)
 Hepatic cancer 1 (0.6%)
 Renal cancer 2 (1.2%)
 Pancreas cancer 1 (0.6%)
 Melanoma 2 (1.2%)
 Prostate cancer 1 (0.6%)
 Esophageal cancer 1 (0.6%)
 Not confirmed 3 (2.0%)
Primary cancer status  
 Progression disease 102 (69.4%)
 Stable, partial regression 40 (27.2%)
 Complete regression 5 (3.4%)
Extracranial metastasis  
 Yes 91 (61.9%)
 No 56 (38.1%)
Characteristics of brain metastasis
Presentation type
 Metachronous 82 (55.8%)
 Synchronous 65 (44.2%)
Number of metastasis  
 Median (range) 2.0 (1–12)
 Single 61 (41.5%)
 2 - 5 58 (39.5%)
 >6 28 (19.0%)
Largest lesion volume (cc)  
 Median (range) 5.1 (0.05-59.9)
 <5 71 (48.3%)
 5-13 55 (37.4%)
 13< 21 (14.3%)
Infratentorial/brain stem  
Involvement  
 No 95 (64.6%)
 Yes 52 (35.4%)
Following WBRT  
 Yes 13 (8.9%)
 No 134 (91.1%)
Sequential systemic chemotherapy  
 Yes 55 (37.4%)
 No 92 (62.6%)
Systemic score
SIRS score  
 Median 4.0
 0 - 3 42 (28.6%)
 4 - 7 105 (71.4%)
GPA score  
 Median 1.5
 0 - 1.5 77 (52.4%)
 2 - 4 70 (47.6%)
RPA class  
 II 126 (85.7%)
 III 21 (14.3%)
BSBM score  
 0 - 1 58 (39.5%)
 2 - 3 89 (60.5%)