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Table 2 Univariate and multivariate analyses of disease-free survival

From: Number of negative lymph nodes is associated with disease-free survival in patients with breast cancer

Characteristic Univariate Multivariate
  HR 95% CI Pvalue HR 95% CI Pvalue
Age       
 <35 1    1   
 ≥35 0.618 0.476-0.803 <0.001* 0.679 0.522-0.883 0.004*
Menopause       
 Premenopause 1     
 Postmenopause 0.995 0.822-1.205 0.960   
pT stage       
 T1 1    1   
 T2 1.699 1.361-2.120 <0.001* 1.361 1.088-1.704 0.007*
 T3 2.844 2.036-3.972 <0.001* 1.585 1.116-2.252 0.010*
 T4 3.150 1.933-5.134 <0.001* 1.798 1.091-2.963 0.021*
pN stage       
 N0 1    1   
 N1 2.187 1.746-2.740 <0.001* 2.083 1.658-2.616 <0.001*
 N2 3.139 2.322-4.244 <0.001* 2.506 1.817-3.456 <0.001*
 N3 6.725 5.236-8.638 <0.001* 4.575 3.315-6.313 <0.001*
ER       
 Negative 1    1   
 Positive 0.586 0.504-0.682 <0.001* 0.720 0.582-0.892 0.003*
PR       
 Negative 1    1   
 Positive 0.620 0.533-0.722 <0.001* 0.790 0.636-0.980 0.032*
Her2       
 Negative 1     
 Positive 0.977 0.871-1.096 0.693   
Number of NLNs (continuous variable) 0.913 0.896-0.930 <0.001* 0.977 0.958-0.997 0.022*
  1. DFS, disease-free survival; HR, hazard ratio; CI, confidence interval; ER estrogen receptor; PR, progesterone receptor; Her-2, human epidermal growth factor receptor-2; NLNs, negative lymph nodes.
  2. *P < 0.05 indicates a significant difference.