S100A14 and S100A16 expression in normal and cancerous breast tissues. A, Representative images of S100A14 and S100A16 protein expression in normal or cancerous breast cancer tissue that was examined using immunohistochemistry. No or faint signals from these proteins were detected in normal epithelial cells of the breast, whereas both proteins were strongly expressed along the cell membrane in about half of breast cancer tissues. B, Kaplan–Meier survival analysis of breast cancer patients. Kaplan–Meier survival curves for patients according to the levels of S100A14 and S100A16 expression are shown.