Table 2 Comparsion of demographic and clinicopathological parameters in sub-cohort I ( “young” , n = 87) versus sub-cohort II ( “old” , n = 125)

age at diagnosis

<50 yr vs. >50 yr

212

<0.001

Sex

male vs. female

212

0.912

Tumor localization

stomach vs. small intestine

187

0.210

GIST histotype

spindle vs. epitheliod/mixed

184

0.426

Tumor size

<1 cm vs. ≥1 cm

199

0.002

<5 cm vs. ≥5 cm

199

0.524

<10 cm vs. ≥10 cm

199

0.605

Mitotic rate

<5 vs. ≥5 / HPF

174

0.902

<10 vs. ≥10 / HPF

173

0.982

Risk acc.to Fletcher et al.

high vs. non-high

180

0.189

Risk acc. to Miettinen et al.

high vs. non-high

167

0.620

R₀resection

yes vs. no

193

0.321

TKI use (imatinib)

yes vs. no

212

0.316

Secondary malignancies

yes vs. no

187

<0.001

Cancer related death

yes vs. no

212

0.017