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Table 2 Comparsion of demographic and clinicopathological parameters in sub-cohort I ( “young” , n = 87) versus sub-cohort II ( “old” , n = 125)

From: Impact of age and gender on tumor related prognosis in gastrointestinal stromal tumors (GIST)

Parameters   n p-value*
age at diagnosis <50 yr vs. >50 yr 212 <0.001
Sex male vs. female 212 0.912
Tumor localization stomach vs. small intestine 187 0.210
GIST histotype spindle vs. epitheliod/mixed 184 0.426
Tumor size <1 cm vs. ≥1 cm 199 0.002
  <5 cm vs. ≥5 cm 199 0.524
  <10 cm vs. ≥10 cm 199 0.605
Mitotic rate <5 vs. ≥5 / HPF 174 0.902
  <10 vs. ≥10 / HPF 173 0.982
Risk acc.to Fletcher et al. high vs. non-high 180 0.189
Risk acc. to Miettinen et al. high vs. non-high 167 0.620
R0resection yes vs. no 193 0.321
TKI use (imatinib) yes vs. no 212 0.316
Secondary malignancies yes vs. no 187 <0.001
Cancer related death yes vs. no 212 0.017
  1. yr, year; HPF, high power field; TKI, tyrosine kinase inhibitor;
  2. *Two-sided χ2-test or Fisher’s exact test were applied as appropriate to check for differences between both study-cohorts.