Arm A | Arm B | |||||||
---|---|---|---|---|---|---|---|---|
(BVZ + CAP + RT) | (CAP + RT) | |||||||
VEGF | VEGFR-2 | Ang-2 | MVD b | VEGF | VEGFR-2 | Ang-2 | MVD b | |
Basal | ||||||||
n | 18 | 18 | 18 | 12 | 23 | 23 | 23 | 18 |
Median | 56 | 9056 | 2424 | 14 | 85 | 9282 | 3609 | 14 |
p | NA | NA | NA | NA | NA | NA | NA | NA |
D15a | ||||||||
n | 18 | 18 | 18 | 12 | 23 | 23 | 23 | 18 |
Median | 13 | 7 | −22 | −8 | −40 | 4 | 16 | 34 |
p | 0.19 | 0.18 | 0.04 | 0.73 | 0.11 | 0.33 | 0.11 | 0.03 |
D57a | ||||||||
n | 14 | 14 | 13 | NA | 17 | 17 | 17 | NA |
Median | 55 | 7 | −16 | NA | −13 | −2 | 20 | NA |
p | 0.03 | 0.20 | 0.20 | NA | 0.71 | 0.86 | 0.01 | NA |