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Table 3 Nonhematologic Toxicity

From: Phase II study of preoperative bevacizumab, capecitabine and radiotherapy for resectable locally-advanced rectal cancer

 

Grade (no. of patients)

Toxicity

1

2

3

4

Asthenia

37

2

0

0

Dhiarrea

26

5

1

0

Hypertension

4

1

0

0

Anorexia

9

0

0

0

Disuria

7

0

0

0

Mucositis

8

0

0

0

Abdominal pain

1

6

0

0

Hand-foot syndrome

11

0

0

0

Vasospastic angina

0

0

0

1

Nauseas

4

0

0

0

Radiodermitis

3

1

1

0

Disphonia

3

0

0

0

Rectitis

2

1

0

0

Stomatitis

2

0

0

0

Vomiting

2

0

0

0

Rectorraghia

1

2

0

0

Anal pruritus

3

0

0

0

Other*

1

0

0

0

  1. Worst grade per patient (n = 41).
  2. *Arthralgia, disphonia, eritema, gastric pain, abdominal discomfort, rash, fever, vomiting, tenesmus (1 each one, grade 1–2).