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Table 3 Nonhematologic Toxicity

From: Phase II study of preoperative bevacizumab, capecitabine and radiotherapy for resectable locally-advanced rectal cancer

  Grade (no. of patients)
Toxicity 1 2 3 4
Asthenia 37 2 0 0
Dhiarrea 26 5 1 0
Hypertension 4 1 0 0
Anorexia 9 0 0 0
Disuria 7 0 0 0
Mucositis 8 0 0 0
Abdominal pain 1 6 0 0
Hand-foot syndrome 11 0 0 0
Vasospastic angina 0 0 0 1
Nauseas 4 0 0 0
Radiodermitis 3 1 1 0
Disphonia 3 0 0 0
Rectitis 2 1 0 0
Stomatitis 2 0 0 0
Vomiting 2 0 0 0
Rectorraghia 1 2 0 0
Anal pruritus 3 0 0 0
Other* 1 0 0 0
  1. Worst grade per patient (n = 41).
  2. *Arthralgia, disphonia, eritema, gastric pain, abdominal discomfort, rash, fever, vomiting, tenesmus (1 each one, grade 1–2).