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Table 1 Comparison of characteristics between pancreatic and non-pancreatic metastasis from RCC (n= 262)

From: Clinical outcome of patients with pancreatic metastases from renal cell cancer

Variables

 

Pancreatic metastasis

Non-pancreatic metastasis

P

Male/female

n (%)

12/8

(60%/40%)

184/58

(76%/24%)

0.11

Age at Dx of RCC*

 

59.7

(52.5–62.5)

61.7

(54.6-69.3)

0.16

Age at Dx of metastasis

 

66.2

(62.3–69.9)

63.6

(56.4-70.2)

0.09

Metastatic sites

n (%)

     
 

Pancreas

20

(100%)

0

(0%)

 
 

Lung

4

(20%)

194

(80%)

<0.0001

 

Bone

0

(0%)

63

(26%)

0.009

 

Kidney

5

(25%)

2

(1%)

<0.0001

 

Lymph nodes

3

(15%)

77

(32%)

0.117

 

Liver

3

(15%)

19

(8%)

0.268

 

Adrenal gland

2

(10%)

39

(16%)

0.469

Synchronous: metachronous (n)

 

3 /17

(15%/85%)

153/89

(63%/37%)

<0.0001

Period from Dx of RCC to metastasis (years)*

 

7.8

(4.2–12.7)

0

(0–0.7)

<0.0001

Metastasectomy (n)

(Yes/No)

15/5

(75%/25%)

56/186

(23%/77%)

<0.0001

Molecular targeted therapy (n)

(Yes/No)

6/14

(30%/70%)

98/144

(40%/60%)

0.357

Median OS from the Dx of metastasis (years)#

 

Not reached

 

2.7

(1.8-3.6)

<0.0001

  1. *Numbers represent Median (IQR), #Numbers represent Median (95% CI), Dx, diagnosis; IQR, inter-quartile range; RCC, renal cell cancer; OS, overall survival; 95% CI, 95% confidence interval.