Figure 4
From: Impact of diabetes type II and chronic inflammation on pancreatic cancer
Diabetes does not inhibit cell death in PDA on day 20. (A) Representative image of an Apoptag+ cell. (B) Quantification of apoptotic cell death in the carcinomas of sham treated non-diabetic (lean Sham) or diabetic (obese Sham) mice and in the carcinomas of cerulein treated non-diabetic (lean Cer) or diabetic (obese Cer) animals. (C) Representative image of a necrotic area. (D) Comparison of the percentage of necrotic tissue area in the carcinomas of the indicated mouse cohorts. Box plots indicate the median, the 25th and 75th percentiles in the form of a box, and the 10th and 90th percentiles as whiskers. The number of animals evaluated was n = 4 (lean Sham), n = 4 (lean Cer), n = 3 (obese Sham), n = 4 (obese Cer) in panel B and n = 7 (lean Sham), n = 7 (lean Cer), n = 3 (obese Sham), n = 6 (obese Cer) in panel D. Differences between the cohorts were not significant. Bar = 50 μm.