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Figure 4 | BMC Cancer

Figure 4

From: Melan-A/MART-1 immunity in a EWS-ATF1 translocated clear cell sarcoma patient treated with sunitinib: a case report

Figure 4

Frequency of circulating mMDSCs and T cell function during sunitinib treatment. Histograms show the frequencies of CD14+HLADRneg/low (mMDSCs) in live gated CD14+CD11b+ cells of patient’s PBMCs. Average level of mMDSC frequency of healthy donors (HD) is reported. Patient’s PBMCs were assayed for IFN-γ (red line) and IL-2 (blue line) production in response to overnight activation with anti-CD3/CD28-coated beads. Dotted horizontal lines (IFN-γ (red) and IL-2 (blue)) indicate the average level of cytokine-producing T cells in HD.

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