Figure 6

Associations between FEN1, YY1 protein, or their combination and OS or DFS. A. FEN1 Kaplan Meier survival plot with breast cancer patient cohort in the Ivshina data base. The black line indicates FEN1 high expression while the red line indicates FEN1 low expression (‘high’ and ‘low’ determined by median expression). Patients with FEN1 high expression: 132; patients with FEN1 low expression: 117, Log-rank p = 0.0007. B. Low expression of YY1 and high expression of FEN1 and OS in the CMU cohort. The black line indicates YY1 low but FEN1 high expression and red line indicates other types. Patients with YY1 low but FEN1 high expression: 154; patients with other types: 113, Log-rank p = 0.027. C. Low expression of YY1 and high expression of FEN1 and DFS in the CMU cohort. The black line indicates YY1 low but FEN1 high expression and red line indicates other types. Patients with YY1 low but FEN1 high expression: 154; patients with other type: 113, Log-rank p = 0.048.