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Table 1 Scoring of immunohistochemical staining of OC cells

From: Melatonin attenuates the TLR4-mediated inflammatory response through MyD88- and TRIF-dependent signaling pathways in an in vivo model of ovarian cancer

  Treatments
OC OC + Mel OC + EtOH OC + EtOH + Mel
TLR2 + ++ + 0
TLR4 +++ + +++ ++
MyD88 ++ 0 ++ +
IKK-α + 0 ++ ++
IkBα ++/+++ 0/+ ++/+++ 0/+
NFkB p65 +++ 0/+ +++ ++
TRAF6 ++ + + +
TRIF +/++ + +/++ +
IRF3 +++ ++ +++ ++/+++
  1. OC staining were interpreted by pathologist visual scoring as 0 (no staining), + (<10% of carcinoma staining), ++ (10-50% of carcinoma staining), or +++ (>50% of carcinoma staining). N = 10 animals/group. Five selected OC sections were analyzed per animal.