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Table 1 Scoring of immunohistochemical staining of OC cells

From: Melatonin attenuates the TLR4-mediated inflammatory response through MyD88- and TRIF-dependent signaling pathways in an in vivo model of ovarian cancer

 

Treatments

OC

OC + Mel

OC + EtOH

OC + EtOH + Mel

TLR2

+

++

+

0

TLR4

+++

+

+++

++

MyD88

++

0

++

+

IKK-α

+

0

++

++

IkBα

++/+++

0/+

++/+++

0/+

NFkB p65

+++

0/+

+++

++

TRAF6

++

+

+

+

TRIF

+/++

+

+/++

+

IRF3

+++

++

+++

++/+++

  1. OC staining were interpreted by pathologist visual scoring as 0 (no staining), + (<10% of carcinoma staining), ++ (10-50% of carcinoma staining), or +++ (>50% of carcinoma staining). N = 10 animals/group. Five selected OC sections were analyzed per animal.