Table 4 Sensitivity and specificity of serum HE4 and CA125 measured during post treatment surveillance in detecting recurrent endometrial cancer
From: Serum HE4 detects recurrent endometrial cancer in patients undergoing routine clinical surveillance
All patients (n = 98) | ||
|---|---|---|
HE4 > 70 | CA125 > 35 | |
Sensitivity | 0.81 | 0.46 |
Specificity | 0.64 | 0.92 |
PPV | 0.45 | 0.67 |
NPV | 0.90 | 0.83 |
Overall accuracy | 0.69 | 0.80 |
Endometrioid histology (n = 69) | ||
HE4 > 70 | CA125 > 35 | |
Sensitivity | 0.84 | 0.42 |
Specificity | 0.74 | 0.92 |
PPV | 0.55 | 0.67 |
NPV | 0.93 | 0.81 |
Overall accuracy | 0.77 | 0.78 |