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Figure 2 | BMC Cancer

Figure 2

From: Cell fusion between gastric epithelial cells and mesenchymal stem cells results in epithelial-to-mesenchymal transition and malignant transformation

Figure 2

DNA ploidy analysis and cell scratch assays. (A) DNA ploidy analysis was performed on the parental and progeny cells. GES-1 and CM-MSCs were diploid. The majority of hybrids were aneuploidy cells (84.10%) (Figure 2A). The remainders were diploid (12.09%) and polyploid (3.81%). (B) Cell scratch results showed that hybrids had stronger migration ability than GES-1 cells. At 24 h, no significant difference was observed, but at 48 h, hybrids migrated toward the center of the scratch and almost filled the area. By 72 h, hybrids migrated toward the center and filled the area. CM-MSCs mirgrated fastest and filled the scratch at 48 h. Magnification: 100×, Scale bar 100 μm. Data are a representative of three experiments.

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