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Table 2 Clinicopathologic characteristics of the 35 lung adenocarcinoma cases

From: MET FISH-positive status predicts short progression-free survival and overall survival after gefitinib treatment in lung adenocarcinoma with EGFR mutation

   

MET gene FISH status

 
   

FISH-negative

FISH-positive

p-value

 

Total

%

Total

%

Total

%

 

Variables

35

100

24

100

11a

100

 

Age

       

<65

13

37

9

38

4

36

 

65≦

22

63

15

63

7

64

1.00

Gender

       

Male

15

43

12

50

3

27

 

Female

20

57

12

50

8

73

0.28

Smoking status

       

Current and former smoker

14

40

10

42

4

36

 

Never smoker

21

60

14

58

7

63

1.00

Stage

       

III

4

11

3

13

1

9

 

IV + Relapse

31

89

21

87

10

91

1.00

EGFR mutation subtype

       

Exon19 deletion

25

71

19

79

6

55

 

Exon21 L858R

10

29

5

21

5

46

0.23

Response to Gefitinib

       

CR + PR

31

89

22

92

9

82

 

SD + PD

4

11

2

8

2

18

0.57

  1. aHigh polysomy was observed in 10 patients (28.5%) and amplification was in 1 patients (2.9%) of 35 NSCLC patients.
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BMC Cancer

ISSN: 1471-2407

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