TOX3 is highly expressed in a subset of LumB tumors and is associated with poor prognosis. A. Examples of TOX3 protein expression in six primary breast cancer samples. B. Proportion of TOX3hi (red) tumors among histologically defined breast cancer subtypes on tissue array of 188 breast tumors. C. Kaplan-Meier plots showing overall survival (OS) and recurrence free survival (RFS) of patients bearing TOX3hi tumors of the LumB and LumA subtypes. Hazard ratios, confidence intervals, and logrank P values are shown.