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Figure 2 | BMC Cancer

Figure 2

From: Development of a semi-conductor sequencing-based panel for genotyping of colon and lung cancer by the Onconetwork consortium

Figure 2

Schematic representation of the results of phase 3 of the panel validation. Indicated are the variants per sample identified in the 28 CRC (A) and 59 NSCLC (B) samples. Variant frequencies were extrapolated to 100% neoplastic cells and/or related to other variants present in the sample (intra-sample comparison). Variants in black correspond to ‘driver’ mutations (present in >35% of neoplastic alleles), while variants in grey are present in only a minority of the neoplastic cells (<35% of neoplastic alleles or an allele frequency 0.5x that of the driver mutation present in the sample). Genes containing >1 variant in different frequencies are indicated in grey/black boxes.

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