Skip to main content
Figure 2 | BMC Cancer

Figure 2

From: Molecular characteristics of endometrial cancer coexisting with peritoneal malignant mesothelioma in Li-Fraumeni-like syndrome

Figure 2

Schematic representation of the genomic alterations in endometrial cancer (Em Ca, the upper panel) and peritoneal malignant mesothelioma (PMM, the lower panel) detected with molecular inversion probe microarrays. (A) Copy number gains are shown in blue and losses in red. The genomic regions with loss of heterozygosity are marked in yellow color. Important genes with high frequency of amplification reported in The Cancer Genome Atlas Research dataset of endometrial cancer are also present in this case. (B) Detailed genomic alterations are shown in chromosome 10q23-2-23.31, where a tumor suppressor gene PTEN was deleted in endometrial cancer. (C) Detailed genomic alterations are shown in chromosome 19q12, where cyclin E1 gene (CCNE1) was amplified in endometrial cancer.

Back to article page