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Figure 5 | BMC Cancer

Figure 5

From: STK33 overexpression in hypopharyngeal squamous cell carcinoma: possible role in tumorigenesis

Figure 5

Effects of STK33-RNAi and PD98059 on migratory and invasive abilities of Fadu cells and relevant genes. Representative images of cystal violet-stained migratory (A) and invasive (B) cells after exposure to the scrambled RNAi and STK33-RNAi, respectively (Magnification × 100, Scale bars, 50 μm). a) Mock, b) 5 μM PD98059, c) STK33-RNAi, d) STK33-RNAi plus 5 μM PD98059. (C) Numbers of migratory and invasive cells in response to different interventions. STK33-RNAi significantly increased the mRNA (D) and protein (E, F) expressions of E-Cadherin and Nm-23-H1, while, PD98059 enhanced the effects and STK33-RNAi obviously decreased the Vimentin expressions. Results were shown as means ± SEM, n = 3. *P < 0.05.

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