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Figure 6 | BMC Cancer

Figure 6

From: Microfluidic model of ductal carcinoma in situ with 3D, organotypic structure

Figure 6

Second Harmonic Generation (SHG) imaging of collagen modifications by invasive clusters. Multiphoton image of a DCIS model cocultured with HMFs. Cells were stained with phalloidin to mark f-actin (shown in red). Using SHG imaging we are able to identify increased collagen I (show in white) modification near the invasive region compared to non-invasive regions. Scale bar represents 100 μm.

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