Table 2 Summary of results section “Soluble factors from breast cancer cells influence macrophage activation”
Cell lines | 3T3 | 4T1 | J774 Macrophages + CM | |||||
|---|---|---|---|---|---|---|---|---|
Markers | 3T3 | 4T1 | LPS | 3T3 LPS | 4T1 LPS | |||
M1 | iNOS/NO2- | +++/ND* | +++/ND | ≈CTR/≈CTR | ≈CTR/≈CTR | >CTR/>CTR | ≈CTR/≈CTR | >CTR/>CTR * |
<LPS/≈LPS | ||||||||
TNF-α (protein) | - | ++ | ≈CTR | ≈CTR | >CTR | >CTR | >CTR | |
≈LPS | ≈LPS | |||||||
IL-6 (mRNA /protein) | +++/+++ | +++/+++ | ≈CTR/≈CTR | <CTR/≈CTR | >CTR/>CTR | >CTR/>CTR | ||
<LPS/≈LPS | ||||||||
IL-12 (mRNA /protein) | ++/++ | ++/++ | ≈CTR/≈CTR | <CTR/ND | >CTR/ND | >CTR/ND | >CTR/ND | |
≈LPS/ND | ≈LPS/ND | |||||||
M2 | MMP-9 (mRNA /protein) | +++/++ | +++/+++ | ≈CTR/≈CTR | ≈CTR/≈CTR | ≈CTR/<CTR | >CTR/≈CTR | ≈CTR/≈CTR |
≈LPS/>LPS | ≈LPS/>LPS | |||||||
VEGF (protein) | +++ | ++ | >CTR | ≈CTR | ≈CTR | >CTR | <CTR | |
>LPS | ≈LPS | |||||||
IL-10 (protein) | + | ++ | ≈CTR | ≈CTR | >CTR | >CTR | >CTR | |
≈LPS | <LPS | |||||||
M-CSF (protein) | ++ | +++ | ≈CTR | ≈CTR | ≈CTR | >CTR | >CTR | |
≈LPS | >LPS | |||||||
MCP-1 (protein) | ++ | +++ | ≈CTR | >CTR | >CTR | >CTR | >CTR | |
≈LPS | ≈LPS | |||||||