Figure 2From: The novel histone deacetylase inhibitor, N-hydroxy-7-(2-naphthylthio) hepatonomide, exhibits potent antitumor activity due to cytochrome-c-release-mediated apoptosis in renal cell carcinoma cellsHNHA suppressed RCC tumor cell proliferation. Cell viability and cell adhesion assays showed that HNHA induced the greatest inhibition of tumor cell proliferation in Caki-1 (A-C) and A-498 cells (D-F) Points indicate mean % of the solvent-treated control. (A, D) and (B, E) experiments were repeated at least three times with similar results. *P < 0.05 vs. Control, **P < 0.01 vs. Control, ***P < 0.005 vs. Control.Back to article page