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Table 6 directionality P values

From: Staged stromal extracellular 3D matrices differentially regulate breast cancer cell responses through PI3K and beta1-integrins

Sample 2D 3D Ctrl Wt 10 nM Wt 50 nM mAb13 mAb13 + Wt 10 nM mAb13 Wt 50 nM
untreated
Ctrl < 0.0014** - 0.0219* < 0.0001*** 0.2395 0.6252 0.0377*
TA < 0.0001*** 0.0109* 0.6641 0.5551 < 0.0001*** < 0.0001*** < 0.0001***
Wt 10 nM
Ctrl - - - 0.3691 0.0545 0.0109* 0.1144
TA - - - 0.3983 < 0.0001*** < 0.0001*** < 0.0001***
Wt 50 nM
Ctrl - - - - 0.0002*** < 0.0001*** 0.0004***
TA - - - - < 0.0001*** < 0.0001*** < 0.0001***
mAb13
Ctrl - - - - - 0.2808 0.5132
TA - - - - - 0.4318 0.2500
mAb13 + Wt 10 nM
Ctrl - - - - - - 0.0568
TA - - - - - - 0.8769
  1. P values were obtained using Mann-Whitney test. Non-significant values are underlined while relative significance levels are designated as extremely***, very**, or significant*. Bolded data represent conditions in which differences were observed between control and tumor-associated 3D matrix induced directionality due to stated treatments.