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Table 1 3D matrix induced morphology measurements; EFF ±

From: Staged stromal extracellular 3D matrices differentially regulate breast cancer cell responses through PI3K and beta1-integrins

substrate

2D

control 3D

tumor-associated 3D

treatment

Ctrl

Ctrl

Wt 10 nM

Wt 50 nM

mAb13

mAb13 +Wt 10 nM

mAb13 +Wt 50 nM

Ctrl

Wt 10 nM

Wt 50 nM

mAb13

mAb13 +Wt 10 nM

mAb13 +Wt 50 nM

Median (mEFF)

1.5

1.7

1.5

1.4

1.4

1.3

1.3

2.2

2.3

1.6

1.4

1.4

1.3

Sample Size

172

251

192

294

173

130

221

292

210

290

206

181

248

Std. Err

0.1

0.1

0.1

0.1

0.1

0.1

0.0

0.1

0.1

0.1

0.1

0.1

0.0

  1. ±EFF = elliptical form factor ratio.