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Table 2 Comparison between protein expression by IHC and gene amplification by CISH and FISH.

From: Quantitative real-time RT-PCR and chromogenic in situ hybridization: precise methods to detect HER-2 status in breast carcinoma

 

CISH (n = 37)

FISH (n = 8)

IHC

No amplification (%)

High amplification (%)

No amplification (%)

Amplification (%)

0 or 1+

22 (84.6)

4 (15.4)

0 (0.0)

0 (0.0)

2+

2 (50.0)

2 (50.0)

0 (0.0)

2 (25.0)

3+

0 (0.0)

7 (100)

0 (0.0)

6 (75.0)

Total

24

13

0

8