Skip to main content
Figure 1 | BMC Cancer

Figure 1

From: Self-renewal and chemotherapy resistance of p75NTR positive cells in esophageal squamous cell carcinomas

Figure 1

Parallel sections from normal esophageal epithelial and ESCC specimen. (A) In NEE, p75NTR was located mainly in the basal layer; in WDC, p75NTR positive staining was apparent in the first one to two layers from the infiltrative margin, areas exhibiting stratified squamous pearl formation were negative for p75NTR; in MDC, p75NTR was expressed in wider range from the margin of the tumors; p75NTR was diffusely distributed in PDC.(B) In NEE, basal cells coexpressed p75NTR and p63, and very few p75NTR+ cells expressed ki-67; in WDC and MDC, p75NTR+ cells were at some distance surrounding involucrin+cells where most of the cells were coexpressed p63, and a small proportion of p75NTR+ cells expressed ki-67; in PDC, few cells were positive for involucrin, more cells contained both p63 and p75NTR, and their distribution was chaotic, a large number of p75NTR+ cells stained brightly for ki-67. (Bars = 200 μm)

Back to article page