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Table 1 C2-O-sLex was expressed in human primary colorectal adenocarcinomas.

From: The high affinity selectin glycan ligand C2-O-sLex and mRNA transcripts of the core 2 β-1,6-N-acetylglusaminyltransferase (C2GnT1) gene are highly expressed in human colorectal adenocarcinomas

 

CHO-131 mAb staining reactivity in colorectal adenocarcinomas

Differentiation status

0+

1+

2+

3+

Well differentiated

1

10 (5)

5 (4)

6 (5)

Moderately differentiated

13

10 (1)

28 (12)

32 (14)

Poorly differentiated

0

2 (0)

2 (0)

4 (2)

  1. 10 benign adenomas were negative for C2-O-sLex expression by CHO-131 staining. 28 normal tissues were negative for C2-O-sLex expression by CHO-131 staining. The brackets indicate the number of tissues where greater than 50% of the total tumor mass stained positively with CHO-131 mAb.